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. 2017 Aug 23;12(8):e0183565. doi: 10.1371/journal.pone.0183565

Table 1. The mean escape latency time in Morris water maze.

Groups Mean escape latency time in MWM (sec)
1st day 2nd day 3rd day 4th day
Vehicle 45.57±1.26 31.11b±1.40 22.125 b±2.32 16.84 b±2.05
Met 45.16±2.14 32.47b±2.70 25.27b±2.07 18.83b±2.06
Saxa 47.11± 1.61 27.37b±1.92 21.27b±2.69 16.90b±3.02
D-gal 51.35±1.53 45.36a±1.16 39.51a±1.79 33.80a±1.62
D-gal/Met 46.91±1.28 34.11b±2.08 21.23b±1.47 14.42b±1.18
D-gal/Saxa 50.57± 1.99 41.54a±2.24 29.75b±2.41 22.88b±2.49

MWM, Morris water maze; Vehicle, rats treated with distilled water (1.5 ml/kg/day, s.c); Met, rats treated with metformin (500 mg/kg/day, p.o); Saxa, rats treated with saxagliptin (1 mg/kg/day, p.o); D-gal, rats treated with D-galactose (150 mg/kg/day, s.c); D-gal/Met, rats treated with D-galactose and metformin; D-gal/Saxa, rats treated with D-galactose and saxagliptin. Each value represents mean ± S.E; n = 8.

a Significantly different from Vehicle group on the corresponding day at p < 0.05.

b Significantly different from D-gal group on the corresponding day at p < 0.05.