Table 6.

Effect of PEGylated to unPEGylated phospholipid ratio and PEG molecular weight on physical stability of placebo PEG-NLC post autoclave sterilization.

% of PEG-lipid	DSPE-PEG-1K/2K/5K lipid (mg)	DSPE lipid (mg)	Oleic acid (mg)	GMS (mg)	Result
PEG(1K)-CIP-NLCs
15	22.5	127.5	300	150	Cracked
30	45	105	300	150	Cracked
40	60	90	300	150	Cracked
PEG(2K)-CIP-NLCs
0 (Control)	(0)	150	300	150	Cracked
10	15	135	300	150	Cracked
15	22.5	127.5	300	150	Cracked
25	37.5	112.5	300	150	Cracked
30	45	105	300	150	Droplets
35	52.5	97.5	300	150	Droplets
40	60	90	300	150	No change
PEG(5K)-CIP-NLCs
15	22.5	127.5	300	150	Cracked
30	45	105	300	150	No change