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. 2017 Aug 11;15(8):e2002527. doi: 10.1371/journal.pbio.2002527

Fig 2. Synteny map of the MAT loci in Cryptococcus amylolentus and closely related species.

Fig 2

Shown at the top and the bottom are results of synteny analyses between sequences from strains CBS6039 and CBS6273 for the HD and P/R loci, respectively. Red color highlights the genes that define the HD locus (SXI1 and SXI2) and P/R locus (mating pheromones and STE3); blue and gray colors highlight the genes that are present or absent from the mating type (MAT) locus in the human pathogenic Cryptococcus species complex, respectively. Shown in the middle are results of dot plot analyses between strains CBS6039 and CBS6273 for the chromosomal regions encompassing the genes that define the HD (SXI1 and SXI2) and P/R (mating pheromone and STE3) loci, respectively. Compared to the flanking regions showing complete synteny between strains CBS6039 and CBS6273, the regions highlighted in green (CBS6039 chromosome 11:155396–177087) and red (CBS6039 chromosome 10:624796–720709) exhibit significantly elevated levels of sequence divergence and chromosomal rearrangements, and define the HD and P/R loci, respectively, in C. amylolentus.