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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Bioorg Med Chem Lett. 2017 Jul 12;27(17):4133–4139. doi: 10.1016/j.bmcl.2017.07.035

Table 3.

Summary of virtual ligand screening, thermal shift assay and binding parameters for the hits obtained after initial seeding with known binders of myoc-OLF from the previous round of virtual screening.

Molecules Tm (°C) ΔTm KD (approx.)(M)
NSC201634 83.79 ~32* 8.0 × 10−12
NSC80735 62.86 11.2 6.5 × 10−7
NSC46492 57.96 6.3 1.1 × 10−5

S. No., serial number; NA, not applicable,

*

The confidence interval of the curve was too wide and hence the estimate represents an approximate fit.