. Author manuscript; available in PMC: 2018 Sep 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2017 May 10;331:54–61. doi: 10.1016/j.taap.2017.05.008

Table 1.

Synergistic cytotoxic effect of 2 μM ATO combination with FK866 on OSCC cells.

Time (h)	Decreased cell survival rate (%)
	SCC15			SCC25
	ATO	FK866	ATO + FK866	ATO	FK866	ATO+ FK866
24	8.1 ± 0.4 ^*	15.4 ± 0.8 ^*	25.4 ± 1.3 ^**	5.2 ± 0.3 ^*	19.9 ± 1.0 ^*	22.6 ± 1.1^*
48	9.1 ± 0.5 ^*	16.3 ± 0.8 ^*	28.6 ± 1.4 ^**	6.4 ± 0.3 ^*	22.3 ± 1.1 ^**	33.7 ± 1.7 ^**
72	22.5 ± 1.1 ^**	16.6 ± 0.8 ^**	46.3 ± 2.3 ^**	26.2 ± 1.3 ^**	16.5 ± 0.8 ^**	53.5 ± 2.7 ^**

After exposure to 2 μM ATO and/or 10 nM FK866 for 24, 48, and 72 h, respectively, the cell survival rate of SCC15 and SCC25 cells was examined. Data represent mean ± SEM.

p < 0.05 and

^**

p < 0.01 compared with untreated cells.