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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: J Immunol. 2017 Jul 26;199(5):1886–1897. doi: 10.4049/jimmunol.1601066

Figure 5. TNF mediates T cell-induced IEC activation in the colon.

Figure 5

(A) Representative images of H&E, BrdU, cleaved caspase-3, and survivin staining of control and anti-CD3 mAb-treated WT and Tnf−/− colon at 24 hours. (B) Quantification of BrdU-, cleaved caspase-3- and survivin-positive IEC detected per crypt. Positive cells were counted in at least 20 well-oriented crypts per section; n=6–8 mice per group. Values represent mean ± SEM, *p<0.05.