Table 2.
Summary of Efficacy Results Before First Progression
| Measure | Patients Treated Beyond Progression (n = 36) |
Patients Not Treated Beyond Progression (n = 92)a |
|---|---|---|
| Objective response rate, No. (% [95% CI]) | 5 (14 [5–30]) | 15 (16 [9–26]) |
| Time to objective response, median (range), mo | 4.2 (1.4–6.9) | 2.6 (1.2–5.6) |
| Best overall response, No. (%) | ||
| Complete response | 0 | 1 (1) |
| Partial response | 5 (14) | 14 (15) |
| Stable disease | 21 (58) | 35 (38) |
| Progressive disease | 9 (25) | 38 (41) |
| Other | 1 (3) | 4 (4) |
| Progression-free survival, median (95% CI), mo | 4.2 (2.8–5.5) | 2.6 (1.5–3.9) |
a
Percentages may not sum to 100 because of rounding.