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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: Nat Med. 2017 Apr 7;23(4):405–408. doi: 10.1038/nm.4306

Figure 2. Repurposing Library contents.

Figure 2

A) Highest clinical phase achieved by each compound. 3,422 drugs in the Library have reached clinical use as of November 2016. B) Number of compounds per target category. Compounds with multiple targets may be indicated in more than one category. C) Number of approved drugs for indications within each listed disease area. D) Classification of proteins targeted by Library drugs. Protein function hierarchy is shown with increasing specificity of function corresponding to distance from the figure center. The relative area of each segment is proportional to the fraction of the Repurposing Library targeting each protein class. As expected, the Library is enriched in drugs targeting kinases, GPCRs, and ion channels.