Table 1.

More than 15 anti-GP (EBOV) full-length mAbs have been described in the literature. The level of conservation among different Zaire EBOV strains varies from 76% to 100%. Among them, examples of linear and conformational epitopes can be found. Z(Zaire), S(Sudan), IC(Ivory Coast).

mAb	Target AA sequence	Specific strain: GP region	Percentage of conservation	Epitope type (linear or conformational)	Reference
1H3	267–281	Z: GP1, sGP	100%	Conformational	(Qiu et al., 2011)
2G4	501–515	Z: GP1, GP2	93.3%	Conformational	(Qiu et al., 2011)
4G7	501–515	Z: GP1, GP2	93.3%	Linear	(Qiu et al., 2011)
5D2	329–343	Z: GP1	73.3%	Linear	(Qiu et al., 2011)
5E6	401–415	Z: GP1	80%	Linear	(Qiu et al., 2011)
7C9	157–369	Z: GP1	91.5%	Conformational	(Qiu et al., 2011)
7G4	157–369	Z: GP1	91.5%	Conformational	(Qiu et al., 2011)
10C8	157–369	Z: GP1	91.5%	Conformational	(Qiu et al., 2011)
KZ52	51–52 505–513 549–556	Z: GP1, GP2	100%	Conformational	(Lee et al., 2008)
13F6	401–417	Z: GP1	76.4%	Linear	(Wilson et al., 2000)
6D8	389–405	Z: GP1	82.4%	Linear	(Wilson et al., 2000)
12B5	477–493	Z: GP1	94.1%	Linear	(Wilson et al., 2000)
6E3	401–417	Z: GP1	76.4%	Linear	(Wilson et al., 2000)
13C6	302–479 494–635	Z, S, IC: GP1, sGP	93.6%	Conformational	(Wilson et al., 2000)
6D3	302–479 494–635	Z, S, IC: GP1, GP2	93.6%	Conformational	(Wilson et al., 2000)
133/3.16	521–560	Z: GP1, GP2	97.5%	Conformational	(Takada et al., 2003)
226/8.1	1–232	Z: GP1, sGP, ssGP	97.4%	Conformational	(Takada et al., 2003)
JP3K11	302–479 505–514 549–556	Z: Cleaved GP1	90%	Conformational	(Shedlock et al., 2010)
S9	293–307	Z: GP1, sGP	100%	Linear	(Marceau et al., 2014)