Fig. 2.

a The complete gene-disease network based on MalaCards data. This is a bipartite network with gene and disease nodes, whereby a connection between two diseases is generated via a gene associated with both. The network shown depicts only the more trustworthy disease-gene relationships (“Elite”), as defined in the “Gene-disease network” of the results. b One of the connected components (sub-networks) which exemplifies the utility of this network, by demonstrating that MalaCards performs informative grouping of diseases with common symptoms and etiology, which could be useful for off-label therapy or disease mechanism elucidation