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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: Cell Metab. 2016 Dec 29;25(2):412–427. doi: 10.1016/j.cmet.2016.11.009

Figure 3. Temporal dynamics of cis-reglatory elements associated with KLA repressed-induced genes.

Figure 3

A. UCSC genome browser images illustrating normalized tag counts for H3K4Me2 and H3K27Ac, at the LXR target genes in bone marrow-derived macrophages treated with KLA for 0, 1, 6 and 24 hours.

B. Distribution of RNA Pol II and H3K27Ac tag densities in vicinity of KLA repressed-induced enhancers in bone marrow-derived macrophages treated with KLA for 0, 1, 6, 24 hours.

C. Distribution of GRO-Seq tags at KLA repressed-induced enhancers in thioglycollate-elicited macrophages treated with KLA for 0, 1, 6, 24 hours.

D. Relative distribution of GRO-Seq tags at gene bodies of KLA repressed-induced genes in thioglycollate-elicited macrophages treated with KLA for 0, 1, 6, 24 hours.

E. Sequence motifs enriched at enhancers associated with KLA repressed-induced genes.