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. 2017 Aug 22;12(8):e0183331. doi: 10.1371/journal.pone.0183331

Table 3. Verification results of the ADx-SuperARMS EGFR assays.

Mutation ΔCt value cut-off for positive calling Mean ΔCt value from 0% of mutant in total DNA Mean ΔCt value from 5% of mutant in total DNA Mean ΔCt value from 1% of mutant in total DNA Mean ΔCt value from 0.2% of mutant in total DNA Mean ΔCt value from 0.1% of mutant in total DNA
E19Del 11 No ΔCt 6.3 8.8 10.6 11.6
L858R 11 No ΔCt 6.4 8.1 10.7 11.4
T790M 8 No ΔCt 2.7 4.4 7.2 10.8

EGFR, epidermal growth factor receptor; E19Del: exon 19 deletion.