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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: Am J Med. 2016 Aug 27;129(11 Suppl):S80–S88. doi: 10.1016/j.amjmed.2016.06.009

Figure 5.

Figure 5

Dose-dependent normalization of fibrin diameter with ciraparantag (PER977) in human volunteers treated with edoxaban. Top: Clot fibrin structure pre- and post-ciraparantag (upper and lower photographs represent lower and higher magnification). Bottom: Computer algorithm-based quantification of clot fibrin diameter. IV = intravenous; PO = oral. Reprinted with permission from Massachusetts Medical Society.44