Coordinating Centers	Principal Investigators and Coordinators
Clinical coordinating center
University of Minnesota, Minneapolis, MN (n = 2)	Adnan I. Qureshi, MD–Principal Investigator Nauman Tariq, MD, Afskin A. Divani, MD–Imaging Analysis Jill Novitzke, RN Haitham H. Hussein MD–Study Coordinator
Statistical coordinating center
Medical University of South Carolina, Charleston, SC	Yuko Y. Palesch, PhD–Statistician Renee’ Martin, PhD–Statistician Catherine Dillon–Project Manager
Hospital or Center, City, State	Principal Investigators and Coordinators
University of Medicine and Dentistry of New Jersey, Newark, NJ (n = 33)	Adnan I Qureshi, MD–Neurologist/Neurointensivist Jawad F. Kirmani, MD–Neurologist/Neurointensivist Mustapha A. Ezzeddine, MD–Neurologist/Neurointensivist Ibrahim Mohammad, MD–Neurologist M. Fareed K. Suri, MD–Neurologist Pansy Harris-Lane, RN–Coordinator
Case Western Reserve University, Cleveland, OH (n = 2)	Jose I. Suarez, MD–Neurologist/Neurointensivist Eliahu Feen, MD–Neurologist Warren Selman, MD–Neurosurgeon Christopher Murphy, RN–Coordinator
Columbia University Medical Center, New York, NY (n = 0)	Stephan A. Mayer, MD–Neurologist/Neurointensivist Augusto Parra, MD–Neurologist Kiwon Lee, MD–Neurologist/Neurointensivist Noeleen Ostapkovich, RN–Coordinator
JFK Medical Center, Edison, NJ (n =1)	Nikolaos I. H. Papamitsakis, MD–Neurologist Spozhmy Panezai, MD–Neurologist Chinekwu Anyanwu, MD–Coordinator
Kansas University Medical Center, Kansas City, KS (n = 3)	John Terry, MD–Neurologist/Neurointensivist Kelly Dickerson, RN–Coordinator
Massachusetts General Hospital, Boston, MA (n = 3)	Joshua Goldstein, MD, PhD–Emergency Medicine Lauren Wendell–Coordinator
Ohio State University, Columbus, OH (n = 1)	Yousef M. Mohammad, MD–Neurologist Hoda Jradi–Coordinator
Saint Louis University, Saint Louis, MO (n = 7)	Salvador Cruz-Flores, MD–Neurologist/Neurointensivist Eve Holzemer, RN–Coordinator
University of Southern CA, Los Angeles, CA (n = 1)	Gene Sung, MD–Neurologist/Neurointensivist Vangie Thomson, RN–Coordinator
Via Christi Regional Medical Center, Wichita, KS (n = 7)	As’ad Ehtisham, MD–Neurologist/Neurointensivist Betty Brown, RN–Coordinator

Data and Safety Monitoring Board: William R. Clarke, PhD; Steven Greenberg, MD, PhD; Leslie Ain McClure, PhD; Emmy R. Miller, PhD, RN; J. Paul Muizelaar, MD, PhD; Howard Yonas, MD.

Funding Organization: National Institute of Neurologic Diseases and Stroke (NINDS).