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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: JAMA Surg. 2017 Jul 19;152(7):e171032. doi: 10.1001/jamasurg.2017.1032

Table 3.

Process and Outcome Metrics Before (Pre) and After (Post) Enhanced Recovery After Surgery Implementation for the Colorectal Resection and Hip Fracture Repair Cohorts

Metric No. of Patients Patientsa P Valueb
Pre Post
Colorectal Resection Cohort
Mobility
 Early ambulation 3687 415 (22.3) 1032 (56.5) <.001
 Sustained ambulation 3685 1603 (86.2) 1735 (95.0) <.001
 Time to first ambulation, median (IQR), h 3717 20.3 (13.5–26.1) 10.3 (6.7–18.6) <.001
Nutrition
 No prolonged fast 3767 69 (3.7) 247 (13.2) <.001
 Early nutrition 3767 245 (13.0) 736 (39.2) <.001
 Time to first nutrition, median (IQR), h 3680 27.0 (18.4–54.1) 16.4 (7.0–23.2) <.001
Analgesia and sedation
 Any benzodiazepine use 3767 267 (14.1) 233 (12.4) .12
 Morphine equivalents, median (IQR), mg 3604 52.4 (23.0–102.0) 30.6 (13.9–65.5) <.001
 Mean acceptable pain scores, median (IQR), % 3761 75.9 (60.0–88.7) 73.8 (59.3–88.4) .14
Outcome metrics
 Hospital length of stay, median (IQR), d 3768 5.1 (3.4–7.1) 4.2 (3.1–6.2) <.001
 Hospital mortality 3768 16 (0.9) 6 (0.3) .03
 Discharge to home 3768 1808 (95.7) 1816 (96.7) .10
 30-d Readmission 3768 348 (18.6) 364 (19.4) .50
 Postoperative complications 2406 184 (18.1) 204 (14.7) .02
 Major complications 2406 42 (4.1) 39 (2.8) .08
Hip Fracture Repair Cohort
Process metrics
 Mobility
  Early ambulation 4619 66 (2.8) 481 (21.2) <.001
  Sustained ambulation 4616 356 (15.2) 719 (31.7) <.001
  Time to first ambulation, median (IQR), h 3189 25.3 (18.1–46.4) 17.3 (11.6–25.5) <.001
Nutrition
 No prolonged fast 5002 32 (1.3) 122 (4.9) <.001
 Early nutrition 5002 1134 (45.6) 1436 (57.1) <.001
 Time to first nutrition, median (IQR), h 4915 12.6 (6.5–17.5) 10.3 (4.9–15.7) <.001
Analgesia and sedation
 Any benzodiazepine use 5002 316 (12.7) 251 (10.0) .002
 Morphine equivalents, median (IQR), mg 4887 38.9 (22.0–66.5) 27.0 (13.5–48.3) <.001
 Mean acceptable pain scores, median (IQR), % 4988 68.2 (54.3–82.1) 72.7 (57.1–85.7) <.001
Outcome metrics
 Hospital length of stay, median (IQR), d 5002 3.6 (2.8–4.8) 3.2 (2.6–4.7) <.001
 Hospital mortality 5002 35 (1.4) 42 (1.7) .45
 Discharge to home 5002 541 (21.7) 676 (26.9) <.001
 30-d Readmission 5002 299 (12.2) 342 (13.8) .09
 Postoperative complications 2287 240 (30.8) 375 (24.9) .003
 Major complications 2287 25 (3.2) 56 (3.7) .53

Abbreviation: IQR, interquartile range.

a

Data are presented as number (percentage) of patients unless otherwise indicated. Not all data were available for all patients, so the total denominator differs based on the specific metric.

b

P values are based on χ2 or Wilcoxon rank sum tests.