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. Author manuscript; available in PMC: 2017 Aug 23.
Published in final edited form as: J Immunol. 2016 Nov 16;198(1):257–269. doi: 10.4049/jimmunol.1601200

FIGURE 1.

FIGURE 1

Accumulation of TCR+ DN thymocytes are observed in the absence of Bim. (A) Thymocytes from C57BL/6 (BL/6) or Bim−/− mice (n = 3) were stained with Abs and analyzed by flow cytometry. Numbers in representative dot plots show the frequency (percentage) of corresponding populations. The bar graphs show the frequency and cell numbers of each population from either BL/6 (open bars) or Bim−/− (filled bars) mice. (B) Histograms show the percentage of CD25−CD44− DN thymocytes that express the surface TCRβ-chain. (C) Bar graph shows the percentage of CD25−CD44− DN thymocytes that express surface TCRα-chain (a combination of Abs against Vα2, Vα3.2, Vα8.3, and Vα11) from either BL/6 (open bars) or Bim−/− (filled bars) mice. Results are representative of at least four independent experiments and show mean ± SD. *p < 0.05, **p < 0.01. BL/6, C57BL/6.