Table 5.
Multivariate linear regression tables after adjustment for PDFF
| Regression | DWI-derived Parameter | ||
|---|---|---|---|
| Model | Coefficient | ADC [95% CI] (10−3 mm2/s) | D [95% CI] (10−3 mm2/s) |
| 1 | Steatosis |
−0.06 [−0.09, −0.03] p<0.001 |
−0.36 [−1.66, 0.94] p = 0.58 |
| Fibrosis | 0.01 [−0.02, 0.04] p = 0.37 |
−1.87 [−3.26, −0.47], p = 0.009 |
|
| Lobular Inflammation | 0.01 [−0.04, 0.06], p = 0.82 |
1.54 [−0.94, 4.01] p = 0.22 |
|
| Portal Inflammation | −0.01 [−0.06, 0.04] p = 0.73 |
−1.00 [−3.46, 1.46] p = 0.42 |
|
| Hepatocellular Ballooning | −0.02 [−0.06, 0.02] p = 0.37 |
−0.51 [−2.39, 1.37] p = 0.59 |
|
| 2 | Steatosis | −0.06 [−0.09, −0.04] p < 0.001 |
−0.51 [−1.73, 0.72] p = 0.41 |
| Fibrosis | 0.01 [−0.02, 0.03] p = 0.50 |
−2.17 [−3.40, −0.94] p < 0.001 |
|
| NASH | 0.01 [−0.04, 0.05] p = 0.81 |
2.13 [−0.19, 4.46] p=0.07 |
|
Results of multivariate linear regression post-adjustment for PDFF is shown. The coefficient and significance of the effect is shown for each histologic feature of NAFLD. Coefficients with p < 0.05 are bolded for visibility