Table 4. Performance of the PDH model for the diagnosis of Acanthamoeba and microsporidia keratitis.
| Positive clinical samplesa (n=21) | Results of the PDH model |
Performance of the PDH model, % (95% confidence interval) |
|||||
|---|---|---|---|---|---|---|---|
| Positive | Negative | Sensitivity | Specificity | PPVb | NPVc | ||
| Acanthamoeba keratitis (n=8) | 7 | 1 | 87.5 (56.7–99.1) | 100 (89.1–100) | 100 (68.8–100) | 96.2 (83.5–99.8) | |
| Microsporidia keratitis (n=13) | 13 | 0 | 100 (80.1–100) | 100 (86.7–100) | 100 (80.7–100) | 100 (86.7–100) | |
aPositive sample as determined by the standard microbiological methods or PCR; bPositive predictive value; cNegative predictive value.