Table 2.
Recipient, donor and transplant factors: Multivariable model of early hospitalization
| Factors | Rate ratio (95% confidence interval) | p-value |
|---|---|---|
| Recipient factors | ||
|
| ||
| Age (years) (ref. 18–39) | 0.01* | |
| 40–49 | 0.91 (0.77, 1.07) | 0.25 |
| 50–54 | 0.89 (0.75, 1.05) | 0.15 |
| 55–59 | 0.81 (0.68, 0.95) | 0.01 |
| 60–64 | 0.90 (0.76, 1.07) | 0.25 |
| ≥ 65 | 0.81 (0.69, 0.95) | 0.01 |
|
| ||
| Female | 1.16 (1.08, 1.23) | <0.001 |
|
| ||
| Race | 0.049* | |
| African American | 1.02 (0.91, 1.14) | 0.75 |
| Asian | 0.80 (0.67, 0.96) | 0.02 |
| Hispanic/Latino | 0.97 (0.88, 1.07) | 0.56 |
| Other race | 0.74 (0.55, 1.00) | 0.05 |
|
| ||
| BMI | 1.00 (0.99, 1.00) | 0.05 |
|
| ||
| Diagnosis | 0.04* | |
| Hepatitis C | 1.12 (1.03, 1.21) | 0.006 |
| Cholestatic liver disease | 1.04 (0.91, 1.19) | 0.54 |
| Hepatocellular carcinoma | 1.05 (0.95, 1.16) | 0.35 |
| Other liver disease | 0.96 (0.84, 1.10) | 0.55 |
|
| ||
| On life support at LT | 1.03 (0.84, 1.25) | 0.79 |
|
| ||
| Medical Condition (ref. not hospitalized) | 0.10 | |
| In ICU | 0.98 (0.83, 1.15) | 0.81 |
| Hospitalized (not in ICU) | 1.10 (1.00, 1.21) | 0.05 |
|
| ||
| ESRD at baseline | 1.24 (1.05, 1.47) | 0.01 |
|
| ||
| Diabetes | 1.18 (1.11, 1.26) | <0.001 |
|
| ||
| On dialysis | 1.29 (1.10, 1.52) | 0.002 |
|
| ||
| Ascites (ref. none) | 0.11* | |
| Slight | 1.09 (1.01, 1.19) | 0.04 |
| Moderate | 1.07 (0.97, 1.18) | 0.20 |
|
| ||
| Loge(creatinine) | 1.22 (1.13, 1.31) | <0.001 |
|
| ||
| Loge(bilirubin) | 0.96 (0.92, 1.00) | 0.06 |
|
| ||
| Loge(INR) | 1.07 (0.96, 1.20) | 0.24 |
|
| ||
| Loge(albumin) | 0.83 (0.72, 0.95) | 0.008 |
|
| ||
| Status 1 | 1.21 (0.90, 1.64) | 0.21 |
|
| ||
| Portal vein thrombosis | 0.96 (0.85, 1.08) | 0.49 |
|
| ||
| TIPSS | 1.10 (1.00, 1.21) | 0.05 |
|
| ||
| Donor and transplant factors | ||
|
| ||
| Age (years) (ref. 18–39) | 0.19* | |
|
| ||
| Under 18 | 1.01 (0.88, 1.14) | 0.93 |
|
| ||
| 40–49 | 1.06 (0.97, 1.16) | 0.19 |
|
| ||
| 50–59 | 1.11 (1.01, 1.21) | 0.03 |
|
| ||
| 60–69 | 1.07 (0.96, 1.19) | 0.19 |
|
| ||
| 70 or older | 0.97 (0.84, 1.12) | 0.67 |
|
| ||
| Female | 0.95 (0.87, 1.03) | 0.20 |
|
| ||
| Race (ref. Caucasian) | <0.001* | |
|
| ||
| African American | 1.11 (1.02, 1.21) | 0.01 |
|
| ||
| Asian | 1.55 (1.27, 1.89) | <0.001 |
|
| ||
| Hispanic/Latino | 0.94 (0.86, 1.04) | 0.26 |
|
| ||
| Other race | 0.73 (0.48, 1.11) | 0.14 |
|
| ||
| Height (cm) | 1.00 (0.99, 1.00) | 0.18 |
|
| ||
| Donation after cardiac death | 1.21 (1.05, 1.38) | 0.007 |
|
| ||
| Cause of death (ref. all others) | 0.27* | |
|
| ||
| Anoxia | 1.02 (0.94, 1.12) | 0.60 |
|
| ||
| Cardiovascular accident | 1.07 (0.99, 1.15) | 0.11 |
|
| ||
| Split liver | 1.07 (0.83, 1.39) | 0.58 |
|
| ||
| Donor location (ref. local) | 0.44* | |
|
| ||
| Regional share | 1.00 (0.92, 1.09) | 0.99 |
|
| ||
| National share | 1.09 (0.95, 1.24) | 0.21 |
|
| ||
| Cold ischemia time (hours) | 1.00 (0.99, 1.01) | 0.68 |
*
p-value from overall test of significance for all levels of the factor.