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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Cardiovasc Eng Technol. 2017 Feb 24;9(2):141–150. doi: 10.1007/s13239-017-0296-z

Figure 3. miR-181b is responsible for shear-dependent ECM degradation.

Figure 3

A–B) HAVECs were transfected with miR-181 mimic (181b mimic) or mimic control at 20nM for 24h previous to application of 24h shear-stress conditions either LS or OS. Expression of mir-181b was quantified via qPCR (A), and MMP activity was measured via gelatinase activity (B). n=4, *p<0.05,**p<0.01. C–D) HAVECs were transfected with anti-miR-181b (anti-181b) or anti-miR control at 100nM for 24h previous to application either LS or OS. Expression of mir-181b was quantified via qPCR (C) and MMP activity was measured via gelatinase activity (D).