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. 2017 Aug 23;7:9212. doi: 10.1038/s41598-017-07790-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the microbial community features between pregnant and non-pregnant participants within each CST. Lactobacillus spp. abundance (A), Shannon diversity (B), Chao1 richness (C), Mollicutes prevalence (D), Ureaplasma prevalence (E) and bacterial load (F) were compared between pregnant and non-pregnant women in each CST. For continuous variables (A–C,F), the mean value is plotted with error bars indicating standard deviation. Significant differences (p < 0.05) between pregnant and non-pregnant women within each CST are indicated by an asterisk. p-values in the main panels refer to the comparison between pregnant and non-pregnant women in Lactobacillus-dominated CST (yellow panel) and non-Lactobacillus-dominated CST (blue panel). A comparison of pooled data from all CST is shown in the right-most panel. Statistical tests used are indicated on the right side of the graph.