Table 1.
Sociodemographic, clinical and microbiological characteristics across pregnant and non-pregnant cohort.
| Characteristics | Pregnant | Non-pregnant |
|---|---|---|
| Age 1,* | (n = 182) | (n = 310) |
| (Mean ± SD, Range) | 33.6 ± 4.3 (21–45) | 30.1 ± 7.6 (18.6–49.2) |
| 18–25 | 5 (2.7%) | 111 (36%) |
| 26–35 | 122 (67%) | 131 (42%) |
| 36–49 | 55 (30.2%) | 68 (22%) |
| Body mass index 1 | (n = 182) | (n = 307) |
| (Mean ± SD, Range) | 23.1 ± 4.21 (17–43) | 23.9 ± 5.2 (15–50) |
| Underweight (<18.50) | 7 (3.8%) | 18 (5.8%) |
| Normal weight (18.51–24.9) | 140 (76.9%) | 194 (62.6%) |
| Overweight (25.0–29.9) | 26 (14.3%) | 55 (17.7%) |
| Obese (>30) | 9 (4.9%) | 40 (12.9%) |
| Ethnicity 2 | (n = 182) | (n = 306) |
| White | 117 (64.3%) | 200 (64.5%) |
| East Asian | 26 (14.3%) | 60 (19.4%) |
| South Asian | 13 (7.1%) | 12 (3.9%) |
| Black | 4 (2.2%) | 9 (2.9%) |
| Other/Mixed ethnicity | 22 (12%) | 25 (8%) |
| Smoking 2,* | (n = 182) | (n = 310) |
| Yes | 4 (2.2%) | 39 (12.6%) |
| Alcohol | (n = 182) | (n = 310) |
| Yes | 11 (6%) | no data |
| Unprotected sex 2,* | (in the past 4 days) | (in the past 2 days) |
| Yes | 47 (25.8%) | 45 (14.5%) |
| Nugent category 2,* | (n = 172) | (n = 307) |
| Not consistent with BV | 111 (61%) | 250 (80.6%) |
| Intermediate BV | 36 (20%) | 25 (8%) |
| Consistent with BV | 25 (14%) | 32 (10.3%) |
| CST 2,* | (n = 182) | (n = 310) |
| I | 56 (30.7%) | 156 (50.3%) |
| II | 12 (6.6%) | 0 (0%) |
| III | 30 (16.5%) | 50 (16.1%) |
| IVA | 0 (0%) | 36 (11.6%) |
| IVC | 26 (14.3%) | 22 (7.1%) |
| IVD | 42 (23.0%) | 24 (7.7%) |
| V | 16 (8.8%) | 22 (7.1%) |
| Estimated bacterial load (total copies of 16 S rRNA gene)/swab 1,* | (n = 181) | (n = 309) |
| (Mean ± SD, Range) | 7.77 ± 0.93 (4.89–10.67) | 6.83 ± 1.55 (3.50–10.31) |
| 104 or less | 1 (0.5%) | 47 (15.2%) |
| 105–106 | 27 (15%) | 97 (31.4%) |
| 107–108 | 133 (73.5%) | 146 (47.2%) |
| 109 or more | 20 (11%) | 19 (6.1%) |
| Presence of Mollicutes 2,* | (n = 182) | (n = 310) |
| Yes | 74 (40%) | 217 (70%) |
| Presence of Ureaplasma 2,* | 42 (23%) | 149 (48%) |
| U. parvum | 39 (21.4%) | 127 (41%) |
| U. urealyticum | 3 (1.6%) | 5 (1.6%) |
| Both | 0 (0%) | 1 (0.3%) |
1t-test; 2Chi-square. *Characteristic with significant differences (at 5% level) between pregnant and non-pregnant cohorts.