Table 3.

Comparison of each marker between the benign and early malignant groups.

	Benign (n = 29)	Malignant Stage I or II (n = 15)	P value
Biliary MIC-1 (pg/ml), median (range)	12 (0–2153) (n = 29)	678 (0–4429) (n = 14)	<0.01
Serum MIC-1 (pg/ml), median (range)	1800 (804–7410) (n = 27)	2926 (427–6952) (n = 14)	0.12
Serum CA19-9 (U/ml), median (range)	13 (2–15682) (n = 24)	45.1 (2–10478) (n = 15)	0.02
Serum CEA (ng/ml), median (range)	1.6 (0.6–5.9) (n = 23)	2.0 (0.4–4.9) (n = 15)	0.52

MIC-1, macrophage inhibitory cytokine-1.