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. 2017 Aug 23;7:9239. doi: 10.1038/s41598-017-08946-3

Table 3.

Statistically significant associations between TAS genes polymorphisms and wine descriptors.

Bitterness Czech Republic Italy Czech Republic and Italy
Chr.7 Gene SNP Model Coef. 95% CI P-value Coef. 95% CI P-value Coef. 95% CI P-value
TAS2R38 rs10246939 C/T vs C/C −0.90 (−1.78; −0.01) 0.05 −0.06 (−0.96; 0.84) 0.90 −0.54 (−1.17; 0.09) 0.10
T/T vs C/C −1.12 (−2.11; −0.14) 0.03 −0.97 (−1.96; 0.02) 0.06 −1.08 (−1.78; −0.38) 0.003
rs1726866 T/C vs C/C −1.06 (−1.94; −0.19) 0.02 −0.07 (−0.97; 0.83) 0.89 −0.63 (−1.27; −0.001) 0.05
T/C vs C/C −1.16 (−2.13; −0.18) 0.02 −0.94 (−1.94; 0.05) 0.06 −1.10 (−1.80; −0.40) 0.002
rs713598 G/C vs C/C −0.71 (−1.67; −0.26) 0.15 0.08 (−0.87; 1.03) 0.87 −0.34 (−1.02; 0.34) 0.33
G/G vs C/C −0.91 (−1.93–0.10) 0.08 −0.51 (−1.51; 0.50) 0.32 −0.75 (−1.46; −0.03) 0.04
Sourness Czech Republic Italy Czech Republic and Italy
Chr.7 Gene SNP Model Coef. 95% CI P-value Coef. 95% CI P-value Coef. 95% CI P-value
TAS2R16 rs6466849 A/G vs G/G 1.20 (0.50; 1.91) 0.001 0.61 (−0.14; 1.35) 0.11 0.94 (0.43; 1.46) 0.0003
A/A vs G/G −0.75 (−2.56; 1.05) 0.41 −5.11 (−9.93; 0.28) 0.04 −1.30 (−2.94; 0.34) 0.12
Astringency Czech Republic Italy Czech Republic and Italy
Chr.1 Gene SNP Model Coef. 95% CI P-value Coef. 95% CI P-value Coef. 95% CI P-value
TAS1R2 rs4920566 G/A vs G/G 0.29 (−0.38; 0.96) 0.40 n.a. n.a. n.a. n.a. n.a. n.a.
A/A vs G/G −1.24 (−1.97; −0.50) 0.001 n.a. n.a. n.a. n.a. n.a. n.a.