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. 2017 Aug 23;7:9191. doi: 10.1038/s41598-017-09295-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Experimental design and behavioral data. (A) Disgusted, neutral and happy facial expressions from the Bochumer Emotional Stimulus Set¹⁰ were used. Each facial expression was paired with an unpleasant, neutral or pleasant odor. (B) For each run, subjects were presented with an emotional facial expression (disgusted, neutral or happy) for 1 seconds, followed by an odor (unpleasant, neutral or pleasant) for 4 seconds, which in the following had to be rated for its valence within 4 seconds. Region of interest analysis was conducted for visual presentation of facial expressions before odor presentation. For odor presentation, a whole brain analysis was conducted. (C) Valence ratings revealed a significant main effect of preceding facial expressions on the perceived odor valence. **Signifies a statistically significant difference at the threshold 0.01.