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. 2017 Aug 23;7:9253. doi: 10.1038/s41598-017-10027-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of JPYS decoction on skeletal muscle autophagy/mitophagy pathway in 5/6 nephrectomised rats. (a) Representative Western blot images of LC3B, Beclin1, P62, BNIP3L, PINK1 and Parkin protein expression. Quantification of (b) LC3II/LC3I ration, (c) Beclin1, (d) P62, (e) BNIP3L, (f) PINK1 and (g) Parkin protein levels. GAPDH was used as loading control. Data are expressed as Fold change vs. Sham and reported as means ± SD, n = 6 per group, *P < 0.05, **P < 0.05 between Sham and CKD groups. ^#P < 0.05 between CKD and JPYS groups.