Table 1.
Summary of PamGene IPA analysis.
| Top Canonical Pathway | p-value |
| PTEN Signaling | 1.06E-04 |
| Axonal Guidance Signaling | 1.8E-04 |
| Semaphorin Signaling in Neurons | 9.7E-04 |
| GDNF Family Ligand-receptor Interactions | 1.29E-03 |
| STAT3 Pathway | 1.44E-03 |
| Top Diseases and Bio Functions | |
| Diseases and Disorders | p-value |
| Cancer | 2.06E-03 |
| Respiratory Disease | 2.06E-03 |
| Molecular and Cellular functions | p-value |
| Cell Cycle | 1.03E-03 |
| Cell Death and Survival | 2.06E-03 |
| Cellular Compromise | 2.06E-03 |
| Cellular Response to Therapeutics | 2.06E-03 |
| Cellular Development | 1.23E-02 |
| Top Networks | |
| Associated Network Function | Score* |
| Carbohydrate metabolism, Cellular Function and Maintenance, Cell-To-Cell Signaling and Interaction | 2 |
| Cell Morphology, Hematological System Development and Function, Inflammatory Response | 2 |
| Cellular Movement, Cell Death and Survival, Cancer | 2 |
| Cell Cycle, DNA Replication, Recombination, and Repair, Cancer | 1 |
*The score of top networks is simply a measure of the number of genes significantly different from CBL WT or Mts in a network.