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. 2017 Mar 12;2(1):e000191. doi: 10.1136/bmjsem-2016-000191

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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Superiority of SET compared with placebo in improving inflammatory, immune and metabolic biomarkers in response to exhaustive eccentric exercise. Effect sizes (changes from baseline) at 3 hours after exhaustive eccentric exercise were pooled for stage I, stage II and both stages combined. Pooled biomarkers include creatine kinase, lactate dehydrogenase, lactate, interleukin 6, prostaglandin E2, total oxidative status, total antioxidative status and natural killer cells, and were analysed for the direction of superiority. df, degrees of freedom; MW, Mann-Whitney; N, number; n. def., not defined; p, probability; SET, systemic enzyme therapy.