Table 3.
Donor | Diagnosis | Blood culture result | Recipient (sex/age) | Underlying liver disease(s) | Culture result (specimen)/time to infection onset | Inappropriate antimicrobial/immunosuppressive therapy | Outcome |
D1 | Head trauma | Negative1 | R12 (Female/48 yr) | Polycystic liver disease | K. pneumoniae (Blood and abdominal drainage fluid)/1 d | No/Pred | Patient death and graft loss |
D2 | Head trauma | Negative1 | R23 (Male/38 yr) | Hepatocellular carcinoma and cirrhosis due to hepatitis B virus infection | K. pneumoniae (Blood and abdominal drainage fluid)/1 d | No/FK506 + Pred | Patient and graft survival |
D3 | Head trauma | Not available | R33 (Male/69 yr) | Heredofamilial amyloidosis | E. aerogenes (Blood)/3 d | No/FK506 + Pred | Patient and graft survival |
Donors had a negative result of blood culture after being admitted to the intensive care unit, whereas they did not undergo blood culture within 10 d prior to organ procurement;
Two kidney recipients of graft from the common donor, with this liver recipient having developed organ-space surgical site infection owing to Klebsiella pneumoniae within 20 d following the transplantation;
One kidney recipient of graft from the common donor, with this liver recipient having also developed bloodstream infection owing to the same bacterium immediately after the transplantation.