Figure 2.

Molecular interactions and binding of PPS and heparin to Th2 cytokines as revealed by surface plasmon resonance (SPR) methodology. Data are shown for representative titration experiments showing the capacity of soluble heparin (dashed lines) and PPS (solid lines) to bind (A) IL‐4, (B) IL‐5, and (C) IL‐13 and prevent attachment to a cytokine‐binding detector chip. The experiments were performed on the BIAcore 2000 platform and with a heparinised CM4 flow cell detector 29.