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. Author manuscript; available in PMC: 2017 Aug 24.
Published in final edited form as: Cancer Cell. 2016 Sep 12;30(3):371–373. doi: 10.1016/j.ccell.2016.08.013

Figure 1. Genetically Engineered Mouse Models Studying the Hematopoietic Effects of Deletion or Mutation of Spliceosomal Genes Commonly Mutated in Hematopoietic Malignancies.

Figure 1

Abbreviations: ESE, exonic splicing enhancer; GMP, granulocyte/macrophage progenitor; LSK, lineage− Sca1+ c-Kit+ cells; LT-HSC, long-term hematopoietic stem cells.