Table 2.
Pooled prevalence of S. aureus resistance to different antimicrobial agents in Ethiopia
| Agent | Number of studies | Total no of isolate tested | No of resistant isolate | Pooled AMR prevalence (95% CI) | I2 (p-value) | |
|---|---|---|---|---|---|---|
| 1. | Vancomycin | 19 | 1750 | 132 | 0.11 (0.04,0.20) | 95.34 (P ≤ 0.01) |
| 2. | Methicilin | 26 | 1179 | 843 | 0.47 (0.33,0.61) | 96.82 (P ≤ 0.01) |
| 3. | Ciprofloxacin | 31 | 2254 | 400 | 0.19 (0.13, 0.26) | 93.06(P ≤ 0.01) |
| 4. | Tetracycline | 36 | 3019 | 1982 | 0.62 (0.55, 0.68) | 92.06(P ≤ 0.01) |
| 5. | Cotrimoxazole | 35 | 2825 | 1364 | 0.47 (0.40, 0.55) | 92.85(P ≤ 0.01) |
| 6. | Chloramphenicol | 34 | 2763 | 1128 | 0.37 (0.29,0.45) | 94.28 (P ≤ 0.01) |
| 7. | Erythromycin | 37 | 3828 | 2222 | 0.41 (0.29, 0.54) | 98.28(P ≤ 0.01) |
| 8. | Penicillin | 33 | 2271 | 1627 | 0.76 (0.67, 0.84) | 95.05(P ≤ 0.01) |
| 9. | Clindamycin | 14 | 1445 | 414 | 0.24 (0.12,0.37) | 95.48(P ≤ 0.01) |
| 10. | Carbencillin | 6 | 398 | 184 | 0.34 (0.17,0.54) | 86.89(P ≤ 0.01) |
| 11. | Amoxicillin | 18 | 870 | 660 | 0.77 (0.68,0.85) | 87.44(P ≤ 0.01) |
| 12. | Amoxicillin-clavulanic | 12 | 524 | 166 | 0.30 (0.19,0.43) | 88.64(P ≤ 0.01) |
| 13. | Ampicillin | 27 | 1814 | 1181 | 0.75 (0.65,0.85) | 95.21(P ≤ 0.01) |
| 14. | Gentamycin | 39 | 3348 | 892 | 0.26 (0.18,0.34) | 95.93(P ≤ 0.01) |
| 15. | Ceftriaxone | 28 | 2032 | 626 | 0.34 (0.25,0.43) | 94.02(P ≤ 0.01) |
| 16. | Cephalothin | 15 | 2330 | 785 | 0.30 (0.18,0.43) | 94.02(P ≤ 0.01) |
| 17. | Cefoxitine | 6 | 374 | 101 | 0.27 (0.06, 0.54) | 95.74(P ≤ 0.01) |
| 18. | Doxycline | 14 | 541 | 239 | 0.43 (0.26,0.60) | 93.32(P ≤ 0.01) |
| 19. | Amikacin | 4 | 211 | 62 | 0.23 (0.07,0.44) | 90.42(P ≤ 0.01) |
| 20. | Kanamycin | 7 | 66 | 40 | 0.14 (0.05,0.25) | 79.36(P ≤ 0.01) |
| 21. | Norfloxacilin | 11 | 751 | 186 | 0.25 (0.14,0.38) | 92.79(P ≤ 0.01) |