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. 2017 Aug 23;15:158. doi: 10.1186/s12957-017-1233-1

Table 1.

Characteristics of randomised controlled trials included in the meta-analysis

Study/year Patients no. (I/C) Cancer type Age, mean, years (I/C) Intervention group Control group Primary outcome Secondary outcomes Study design/Jadad score
Type of PR Time/session Frequency Intensity Duration
Arbane et al., [15] 51 (26/25) NSCLC 65.4/62.6 Strength and mobility training 5–10 min Twice daily 60–80% MHR 12 weeks + 5 days Usual care 6MWD POC, QoL, quadriceps strength RCT/4
Arbane et al., [20] 131 (64/67) NSCLC 67/68 Hospital plus home exercise 30 min Once daily 60–90% MHR 4 weeks Usual care Physical activity POC, QoL, quadriceps strength RCT/4
Brocki et al., [43] 78 (41/37) NSCLC 64/65 Aerobic exercise + resistance training + dyspnoea management NA NA 60–80% peak work capacity 12 weeks Usual care QoL 6MWD, FEV1 RCT/3
Brocki et al., [16] 68 (34/34) NSCLC + metastatic tumour + other type 69.7/70.5 Inspiratory muscle training NA Twice daily 30% of MIP 2 weeks Standard physiotherapy treatment Inspiratory muscle strength 6MWD, FEV1, dyspnoea, POC RCT/4
Edvardsen et al., [22] 61 (30/31) NSCLC 64.4/65.9 High-intensity endurance and strength training 60 min Three times a week 80–95% MHR 20 weeks Standard postoperative care Peak oxygen uptake FEV1, QoL, muscular strength and mass RCT/4
Stigt et al., [21] 49 (23/26) NSCLC 63.6/63.2 Aerobic (cycling) + resistance 60 min Twice weekly 60–80% peak load 12 weeks Usual care QoL 6MWD, FEV1, pain RCT/4

I/C intervention/control, NSCLC non-small cell lung cancer; MHR maximum heart rate, 6MWD 6-min walk distance, QoL quality of life, RCT randomised controlled trial, NA not available, FEV 1 the forced expiratory volume in 1 s, MIP maximal inspiratory pressure