Table 2.
Highlighted genes from genome-wide (in bold) and chromosome-wise associations for scrotal circumference at 420 d of age
Symbol | SNP Reference | Chr:Pos | Distances to gene | P-value (Min - Max) |
---|---|---|---|---|
RAP1B | rs110520377 a, rs133990240 a, rs109547215a, rs110160018 b, rs110261691 c, rs109099268 b, rs133124963 b, rs109023687 b, rs110034677 b, rs110091099 b, rs109950552 b, rs137658592 b, rs133340933b, rs134626455b, rs110001336b, rs109288126 b, rs137319832b, rs109506571 b, rs109248631 b, rs110027103 b, rs109561643 b, rs109210079 b, rs110160918 b, rs134366426b, rs109273768b, rs109024096b, rs110798702b, rs110625630 b, rs110219262 b, rs134311132 b, rs135497432 b, rs133173059 b | 5:45.35..45.40 | 8.58..0.00 | 2.47E-07 - 7.64E-05 |
SRGAP1 | rs110268648 b, rs109748105 b, rs134621421 b | 5:49.98..49.98 | 0.00 | 1.88E-06 - 6.55E-06 |
FOXM1 | rs135705262b | 5:107.39 | 0.00 | 4.00E-04 |
TOP1 | rs134822694 b, rs135287766 b | 13:70.39..70.40 | 0.00 | 3.86E-06 |
STAU2 | rs137465376b, rs134711539b, rs137821036a | 14:38.89..38.97 | 0.00..14.40 | 8.66E-05 - 5.00E-04 |
PEX2 | rs137442228d, rs110035827a, rs41730291a | 14:42.33..42.37 | 0.00..40.77 | 4.10E-04 - 9.80E-04 |
FABP5 | rs109480456a, rs136045797a, rs133930486e, rs136613853b, rs137684819c, rs133054550a, rs133483556a, rs136236059a, rs136236059a, rs137344980a, rs135804214a, rs136785030a, rs135727060a, rs133436244a, rs134708967a, rs43103204a | 14:46.63..46.73 | 15.48..0.00..83.31 | 1.55E-05 - 1.16E-03 |
FABP12 | rs43765470b, rs43765465a, rs41730924a | 14:46.89..46.92 | 0.00..28.04 | 3.48E-05 - 2.88E-04 |
MED30 | rs135065691c, rs41734435b, rs135292147a | 14:48.94..48.97 | 4.03..0.00..9.76 | 8.27E-04 - 9.48E-04 |
TRHR | rs133457508e | 14:57.52 | 0.00 | 2.27E-04 |
aintergenic region bintron variant cdownstream variant d5′ UTR eupstream variant
Gene symbols, SNP reference number, and chromosomes (Chr) and positions (Pos, in megabase) were obtained from NCBI website. Distances to gene (kilobase) are presented from 5′ to gene and 3′ to gene directions. If distance equals zero (0.00), the SNP is on intragenic region. P-values are presented as the minimum (Min) and maximum (Max) significance obtained from the generalized quasi-likelihood method