Skip to main content
. Author manuscript; available in PMC: 2017 Aug 24.
Published in final edited form as: J Biomed Nanotechnol. 2017 Apr;13(4):355–366. doi: 10.1166/jbn.2017.2353

Table I.

Solvent systems and electrospinning parameter for FU loaded PCL NFs.

NFs set Category Core solution Sheath solution Applied voltage (KV) Tip to collector distance (mm)


Solvent Solute (mg/ml) Flow rate (ml/hr) Solvent Solute (mg/ml) Flow rate (ml/hr)
Neat PCL 1 Not applicable Not applicable Not applicable DMF 140 mg/ml PCL 1 21 185
A 1 DMF* 50 mg/ml FU 0.2 DMF 140 mg/ml PCL 1 21 185
B 2 FA 50 mg/ml FU, 50 mg/ml PVA§ 0.4 47.5% FA, 47.5%
AA||, 5% TCM
140 mg/ml PCL 1 22 135
C 2 FA 50 mg/ml FU, 50 mg/ml PVA 0.5 47.5% FA, 47.5% AA, 5% TCM 140 mg/ml PCL 1 23.2 110
D 3 FA 50 mg/ml FU 0.2 47.5% FA, 47.5% AA, 5% TCM 140 mg/ml PCL 0.6 19.5 135
E 3 FA 50 mg/ml FU 0.2 47.5% FA, 47.5% AA, 5% TCM 140 mg/ml PCL 0.4 21 135
F 3 FA 50 mg/ml FU 0.2 47.5% FA, 47.5% AA, 5% TCM 140 mg/ml PCL 0.3 19 135
G 3 FA 5 mg/ml Paclitaxel 0.1 47.5% FA, 47.5% AA, 5% TFE# 140 mg/ml PCL 0.6 19.5 135

Notes:

*

Dimethylformamide;

Formic Acid;

5-Fluorouracil;

§

PolyVinyl Alcohol;

||

Acetic acid;

Trichloromethane;

#

Trifluoroethanol.