Figure 5.

MiR-92a induces HCC proliferation and invasion through the inhibition of FOXA2 expression

A) HepG2 cells or Huh7 cells were transfected with FOXA2 plasmid, and the relative level of FOXA2 was examined by qRT-PCR. Each bar represented the mean±SD **P<0.01. B) HepG2 cells were co-transfected with miR-92a and a pcDNA3.1-FOXA2 overexpression plasmid, or control mimics, or miR-92a and pcDNA3.1, or pcDNA3.1-FOXA2. MTT assay was performed in triplicate experiments. *P<0.05. C) MTT assay was performed in Huh7 cells. *P<0.05. D) HepG2 cells were co-transfected with miR-92a and a pcDNA3.1-FOXA2 overexpression plasmid, or control mimics, or miR-92a and pcDNA3.1, or pcDNA3.1-FOXA2, transwell assay was performed, relative statistically analyses were represented. E) The above transwell assay was performed in Huh7 cells