Table A3.

Multivariate Cox Proportional Hazards Models for Predictors of Survival in Experimental Arm

Variable	HR	95% CI	df	P
OS
Pathologic response (favorable v unfavorable)	0.352	0.132 to 0.938	1	.037
Clinical response (response v nonresponse)	0.648	0.297 to 1.413	1	.275
cN stage			2	.052
cN0 v cN1 + cN2	0.361	0.157 to 0.830	1	.016
cN2 v cN1 + cN0	0.610	0.248 to 1.503	1	.283
DFS
Pathologic response (favorable v unfavorable)	0.309	0.118 to 0.808	1	.017
Clinical response (response v nonresponse)	0.529	0.262 to 1.067	1	.075
cN stage			2	.149
cN0 v cN1 + cN2	0.500	0.238 to 1.050	1	.067
cN2 v cN1 + cN0	0.985	0.445 to 2.180	1	.970
Locoregional recurrence–free survival
Pathologic response (favorable v unfavorable)	0.309	0.118 to 0.808	1	.017
Clinical response (response v nonresponse)	0.529	0.262 to 1.067	1	.075
cN stage			2	.149
cN0 v cN1 + cN2	0.500	0.238 to 1.050	1	.067
cN2 v cN1 + cN0	0.985	0.445 to 2.180	1	.970
Distant metastasis–free survival
Pathologic response (favorable v unfavorable)	0.369	0.139 to 0.982	1	.046
Clinical response (response v nonresponse)	0.662	0.304 to 1.442	1	.299
cN stage			2	.057
cN0 v cN1 + cN2	0.368	0.160 to 0.845	1	.018
cN2 v cN1 + cN0	0.610	0.248 to 1.500	1	.282

Abbreviations: DFS, disease-free survival; HR, hazard ratio; OS, overall survival.