Effect of PGRPLB RNAi on the local and systemic activation of the Imd pathway. a, b, d, eCEC1 expression in the midguts (a, d) and fat bodies (b, e) of mosquitoes after injection of PGRPLB or LacZ control dsRNA in sugar-fed (SF; a, b) or blood-fed (BF; d, e) conditions. cPGRPLB expression in sugar-fed mosquitoes or 24 h after blood feeding. Statistical data show the results of ANOVA following a common linear regression model fitting. ·p < 0.1; * p < 0.05; ** p < 0.01; *** p < 0.001.