| Year | All AF (n) | Contraindications (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Any | Adverse reaction | Peptic ulcer | Major bleeding | Haemorrhagic stroke | Hypertension | Oesophageal varices | Aneurysm | Proliferative retinopathy | Pregnancy | ||
| 2004 | 45 329 | 6.55 | 0.11 | 0.64 | 4.80 | 0.31 | 0.22 | 0.04 | 0.66 | 0.04 | 0.01 |
| 2005 | 51 172 | 6.41 | 0.17 | 0.55 | 4.74 | 0.33 | 0.16 | 0.04 | 0.67 | 0.05 | 0.00 |
| 2006 | 55 939 | 6.26 | 0.17 | 0.51 | 4.60 | 0.34 | 0.11 | 0.03 | 0.71 | 0.05 | 0.00 |
| 2007 | 58 495 | 5.96 | 0.15 | 0.49 | 4.38 | 0.33 | 0.09 | 0.02 | 0.69 | 0.04 | 0.00 |
| 2008 | 61 526 | 5.87 | 0.16 | 0.49 | 4.33 | 0.30 | 0.06 | 0.03 | 0.67 | 0.04 | 0.00 |
| 2009 | 65 552 | 6.05 | 0.14 | 0.46 | 4.53 | 0.27 | 0.06 | 0.03 | 0.75 | 0.04 | 0.01 |
| 2010 | 66 445 | 6.06 | 0.14 | 0.37 | 4.58 | 0.29 | 0.06 | 0.03 | 0.77 | 0.06 | 0.00 |
| 2011 | 68 193 | 6.02 | 0.13 | 0.43 | 4.55 | 0.30 | 0.05 | 0.03 | 0.70 | 0.05 | 0.00 |
| 2012 | 69 653 | 6.10 | 0.10 | 0.44 | 4.60 | 0.32 | 0.04 | 0.03 | 0.74 | 0.05 | 0.01 |
| 2013 | 69 233 | 6.14 | 0.13 | 0.40 | 4.60 | 0.35 | 0.03 | 0.03 | 0.75 | 0.04 | 0.01 |
| 2014 | 66 948 | 6.11 | 0.14 | 0.36 | 4.59 | 0.40 | 0.02 | 0.03 | 0.75 | 0.03 | 0.00 |
| 2015 | 57 453 | 5.84 | 0.12 | 0.35 | 4.39 | 0.37 | 0.02 | 0.03 | 0.70 | 0.03 | 0.00 |