Table 5.
Difference in costs (in €, 2012–2014) for each medication group for partially adherent and non-adherent patients in comparison with initially adherent patients based on adjusted multilevel regression analysis
| Cost, € | All medications, mean (95% CI) | Chronic, mean (95% CI) | Analgesics, mean (95% CI) | Penicillins, mean (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
| Partially adherent | Initially non-adherent | Partially adherent | Initially non-adherent | Partially adherent | Initially non-adherent | Partially adherent | Initially non-adherent | |
| Medical cost | −2.02 (−4.79 to 0.76) | −10.54a (−12.62 to −8.46) | −16.35a (−31.22 to −1.47) | −34.51a (−40.84 to −28.18) | 8.07a (3.60 to 12.57) | −12.54a (−14.82 to −10.26) | −12.51 (−29.56 to 4.54) | −6.84a (−13.42 to −0.27) |
| Drug cost | −22.59a (−24.21 to −20.97) | −15.38a (−16.41 to −14.35) | −62.03a (−73.17 to −50.89) | −55.75a (−55.75 to −48.60) | −6.40a (−8.29 to −4.52) | −7.49a (−8.48 to −6.49) | −10.99a (−19.17 to −3.47) | −3.21a (−6.04 to −0.38) |
| Sick leave cost (minimum salary) | 80.90a (73.54 to 88.26) | 52.99a (47.68 to 58.31) | 39.97a (11.87 to 68.05) | 44.30a (29.90 to 58.70) | 80.62a (70.00 to 91.26) | 57.91a (51.81 to 64.02) | 67.20a (32.13 to 102.27) | 85.20a (70.42 to 99.97) |
| Sick leave cost (mean salary) | 244.89a (222.61 to 267.17) | 160.42a (144.32 to 176.50) | 120.96a (35.93 to 205.99) | 134.10a (90.50 to 177.69) | 244.05a (211.88 to 276.23) | 175.30a (156.81 to 193.79) | 203.42a (97.26 to 309.58) | 257.89a (213.16 to 302.61) |
| Total cost (minimum salary for sick leave) | 34.56a (25.48 to 43.63) | 2.58 (−3.82 to 8.98) | −49.55a (−85.90 to −13.20) | −61.76a (−79.65 to −43.86) | 65.21a (52.47 to 77.96) | 14.15a (6.89 to 21.41) | 9.86 (−36.42 to 56.15) | 56.86a (38.05 to 75.67) |
| Total cost (mean salary for sick leave) | 242.12a (218.33 to 265.91) | 164.71a (147.70. to 181.71) | 52.30 (−37.43 to 142.03) | 10.74 (−35.61 to 57.10) | 256.59a (222.78 to 290.40) | 166.60a (149.85 to 186.34) | 144.99a (30.35 to 259.64) | 229.99a (182.60 to 277.37) |
a
Statistically significant differences. PCC = primary care centre.