Fig. 3.

Long-term projected asymptotic body mass gains (A–D) and total final body mass (E–H) show that the AHR antagonist NF (~90 mg/kg/day) significantly reduced Western diet-based body mass gain in female and male B6 and B6.D2 mice over a longer time course. Each experimental group (n≥15) was fed control, control+NF, Western, or Western+NF diet ad libitum for 26 wks beginning at weaning. NF, α-naphthoflavone. Error bars represent SEM.