Fig. 5.

The inclusion of NF (~90 mg/kg/day) ameliorates Western diet-based liver steatosis but increases liver size in female and male B6 and B6.D2 mice. Representative sections stained with Masson’s trichrome from livers of mice fed control, control+NF, Western, or Western+NF diet ad libitum for 26 wks beginning at weaning for B6 female (A–D), B6.D2 female (E–H), B6 male (I–L), and B6.D2 male (M–P) mice. (Q) A plot of liver mass to body mass ratio (n≤15/experimental group). p-values: ** ≤0.01; ***, ≤0.001. NF, α-naphthoflavone. Error bars represent SEM.