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. 2017 May 26;45(13):8014–8025. doi: 10.1093/nar/gkx470

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Scheme 3. — (A) Schematic illustration of RNA isomers and forms, m indicates methylation sites, and (B) calculated isotopic profiles for 20 nt (A₅C₅G₅U₅), 40 nt (A₁₀C₁₀G₁₀U₁₀), and 80 nt (A₂₀C₂₀G₂₀U₂₀) RNA with (open circles) and without (filled circles) a single methylation (+CH₂, 14.0157 Da).