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. 2017 Jun 7;45(13):7581–7592. doi: 10.1093/nar/gkx507

Figure 2.

Figure 2.

Stabilization of the 5΄ end by 5΄-(E)-vinylphosphonate supports RISC loading and activity. (A) Chemical structures of 5΄phosphate (5΄-P) and 5΄-(E)-vinylphosphonate (5΄-VP). (B) Except that HeLa cells treated with 5΄-P or 5΄ -VP modified hsiRNAs, as indicated in the legend.

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