Table 1.
Baseline characteristics by IgG level
| Characteristic | IgG > 375 mg/dL (n = 24) | IgG ≤ 375 mg/dL (n = 6) | P-value |
|---|---|---|---|
| Female, n (%) | 17 (70.8) | 6 (100.0) | 0.29 |
| Caucasian, n (%) | 18 (75.0) | 5 (83.3) | 1.00 |
| Diagnosis, n (%) | |||
| GPA | 14 (58.3) | 2 (33.3) | 0.47 |
| MPA | 8 (33.3) | 4 (66.7) | |
| EGPA | 2 (8.3) | 0 (0.0) | |
| ANCA type, n (%) | |||
| c-ANCA | 12 (50.0) | 1 (16.7) | 0.19 |
| p-ANCA | 11 (45.8) | 4 (66.7) | |
| ANCA negative | 1 (4.2) | 1 (16.7) | |
| Age at RTX, years (SD) | 61.7 (3.0) | 68.7 (4.8) | 0.30 |
| Estimated GFR (SD) | 30.8 (4.3) | 20.2 (2.6) | 0.23 |
| Cyclophosphamide use, n (%) | 6 (25.0) | 3 (50.0) | 0.33 |
| RTX maintenance, n (%) | 12 (50.0) | 4 (66.7) | 0.66 |
| B cell depletion, n (%) | 21 (95.5)a | 4 (66.7) | 0.11 |
a
Two patients in the IgG > 375 mg/dL group were not checked for B cell depletion.