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. 2017 May 12;45(Web Server issue):W276–W284. doi: 10.1093/nar/gkx411

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — PP2A complexes predicted based on GO functional similarities alone and in combination with abundance correlations. (A) PP2A complexes inferred from GO similarities. Similarity values >0.6 were considered as interactions. Proteins were cluster using the MCL algorithm and arranged by a force-layout algorithm as described in (2A). (B) PP2A network analysis by applying abundance correlations combined with GO functional similarities between preys. Combined values >0.65 were considered as interactions. Proteins were clustered using the MCL algorithm and arranged by force-layout algorithm using combined values as interaction strength and the inverse values for node-node initial distances. (C) Zoom-in on complexes detected in (A) and (B).