Table 2.

Hazard ratios (95% confidence intervals) for body mass index, height, and glioblastoma risk

Gender
Women and men
Time at risk (years)	54,869,912
GBM No	3102
BMI per 5 kg/m2 increase	1.00 (0.95–1.06); P = 96
Height per 10 cm increase	1.24 (1.17–1.31); P < 001
BMI category (kg/m2)	<20	20–24.9	25–29.9	≥30
HR (95% CIs)	0.90 (0.78–1.04)	Ref	0.98 (0.90–1.06)	0.96 (0.82–1.11)
Women
Time at risk (years)	29,539,250
GBMs No	1331
BMI per 5 kg/m2 increase	0.98 (0.91–1.05); P =.52
Height per 10 cm increase	1.27 (1.15–1.40); P < 001
BMI category (kg/m2)	<20	20–24.9	25–29.9	≥30
HR (95% CIs)	0.89 (0.73–1.08)	Ref	0.89 (0.78–1.01)	0.92 (0.76–1.11)
Height in quartiles	1.	2.	3.	4.
HR (95% CIs)	Ref	1.03 (0.87–1.21)	1.20 (1.02–1.40)	1.34 (1.14–1.57)
Men
Time at risk (years)	25,330,662
GBM No	1771
BMI per 5 kg/m2 increase	1.04 (0.96–1.13); P =.38
Height per 10 cm increase	1.22 (1.14–1.32); P < 001
BMI category (kg/m2)	<20	20–24.9	25–29.9	≥30
HR (95% CIs)	0.90 (0.73–1.11)	Ref	1.04 (0.94–1.15)	0.96 (0.75–1.24)
Height in quartiles	1.	2.	3.	4.
HR (95% CIs)	Ref	1.34 (1.16–1.54)	1.36 (1.17–1.58)	1.48 (1.28–1.70)

Cox regression model with age as the time axis, including sex (where not stratified), height, BMI and birth year cohort; all P values derived from BMI or height as continuous variables.

Abbreviations: CI s, confidence intervals; HR, hazard ratio; Ref, reference group.