Table 3.
Hazard ratios (95% confidence intervals) for body mass index, height, and risk for gliomas other than glioblastomas
| Gender | ||||
|---|---|---|---|---|
| Women and Men | ||||
| Time at risk (y) | 54,826,767 | |||
| Glioma No | 1,280 | |||
| BMI per 5 kg/m2 increase | 0.96 (0.88–1.05); P = 38 | |||
| Height per 10 cm increase | 1.18 (1.09–1.29); P <.001 | |||
| BMI category (kg/m2) | <20 | 20–24.9 | 25–29.9 | ≥30 |
| HRs (95% CIs) | 1.10 (0.92–1.30) | Ref | 0.99 (0.87–1.14) | 0.92 (0.70–1.21) |
| Women | ||||
| Time at risk (years) | 29,520,716 | |||
| Glioma No | 586 | |||
| BMI per 5 kg/m2 increase | 0.95 (0.85–1.07); P =.41 | |||
| Height per 10 cm increase | 1.20 (1.04–1.38); P =.013 | |||
| BMI category (kg/m2) | <20 | 20–24.9 | 25–29.9 | ≥30 |
| HR (95% CIs) | 0.97 (0.76–1.24) | Ref | 0.96 (0.77–1.18) | 0.83 (0.58–1.18) |
| Height in quartiles | 1. | 2. | 3. | 4. |
| HR (95% CIs) | Ref | 1.14 (0.88–1.48) | 1.16 (0.89–1.50) | 1.34 (1.04–1.71) |
| Men | ||||
| Time at risk (years) | 25,306,052 | |||
| Glioma No | 694 | |||
| BMI per 5 kg/m2 increase | 1.01 (0.88–1.15); P =.91 | |||
| Height per 10 cm increase | 1.17 (1.05–1.31); P =.004 | |||
| BMI category (kg/m2) | <20 | 20–24.9 | 25–29.9 | ≥30 |
| HR (95% CIs) | 1.21 (0.94–1.55) | Ref | 1.04 (0.87–1.24) | 1.18 (0.78–1.78) |
| Height in quartiles | 1. | 2. | 3. | 4. |
| HR (95% CIs) | Ref | 1.16 (0.92–1.46) | 1.26 (0.99–1.59) | 1.33 (1.06–1.66) |
Cox regression model with age as the time axis, including sex (where not stratified), height, BMI, and birth year cohort; all P values derived from BMI or height as continuous variables.
Abbreviations: BMI, body mass index; CIs, confidence intervals; HR, hazard ratio; Ref, reference group.