Table 1. Cα RMSD values of the models produced by the old server (PIGS) and its updated version (PIGSPro).

	All residues	Loop residues: local	Loop residues: global	H3 residues: local	H3 residues: global	Framework residues	Lambda light chains
PIGS	1.36 ± 0.64	2.21 ± 1.48	2.26 ± 1.52	3.59 ± 2.93	3.67 ± 2.92	0.78 ± 0.28	0.89 ± 0.27
PIGSPro	1.16 ± 0.47	1.75 ± 0.95	1.79 ± 1.03	2.41 ± 2.2	2.45 ± 2.18	0.75 ± 0.24	0.83 ± 0.64
Number of models	252	252	252	252	252	252	15

The RMSD for the loop residues and H3 are computed both after superimposing their stems, i.e. the two residues before and after the loop (local) and after superposition the framework (global). Underlined values indicate a statistically significant difference (95% confidence level) with respect to the PIGS method based on an unpaired t-test.