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. 2017 Jun 21;19(9):1248–1254. doi: 10.1093/neuonc/nox066

Table 2.

Clinical manifestations leading to initial evaluation for leptomeningeal metastases

Clinical Manifestations Leading to Initial Evaluation for LM N (%)
Clinical symptoms* 92 (97)
 Headache 32 (34)
 Gait instability 28 (29)
 Sensory changes 24 (25)
 Confusion/mental state changes 22 (23)
 Focal limb weakness 22 (23)
 Cranial nerves abnormalities 16 (17)
 Back pain 9 (9)
 Nausea and vomiting 7 (7)
 Seizures 6 (6)
 Urine incontinence 4 (4)
 Speech abnormalities 3 (3)
MRI abnormalities 3 (3)

*Some patients had more than one clinical symptom.